JmjC: JmjC domain, hydroxylase
| PAG Title | JmjC: JmjC domain, hydroxylase |
| PAG ID | PEX002478 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | The JmjC domain belongs to the Cupin superfamily 3. JmjC-domain proteins may be protein hydroxylases that catalyse a novel histone modification 4. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation 5. |
| Species | Homo sapiens |
| nCoCo Score | 384 |
| Base PAG ID | PEX002478 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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